Multimodal Neuroimaging Study of Sex Differences in Children with Autism Spectrum Disorder

Short Title

Department of Biomedical Engineering, New Jersey Institute of Technology

Project Description

This study aims to examine whether girls with autism have similar or different brain mechanisms as boys.

Girls are less likely to suffer from autism spectrum disorder (ASD). At the same time, girls have been largely overlooked in research of ASD. In this study, we will use several non-invasive brain imaging techniques to study early alterations in brain structure and functions in girls and boys with ASD, as well as making comparisons of the brain with typically developing children. We are particularly interested in studying how different brain regions are connected with each other between the ages of 7-11 years. We want to find out that whether girls with ASD have similar or different brain connectivity patterns compared with boys with ASD. Understanding which sex differences of ASD and the brain regions associated with these changes will provide significant hints as to why females are less likely to suffer from the disorder, and they may also be helpful for identifying early signatures of autism in both girls and boys.

Selection Criteria

  • Age between 7 to 11 years old.
  • girls and boys
  • typically developing and children with ASD
  • Right-handed
  • Do not have histories of any neurological conditions. 
  • Do not have histories of diagnosis with psychiatric disorders other than ASD
  • Do not have metal implants and foreign bodies, pacemakers.
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Team Members

Bharat Biswal
Principal Investigator

Xin Di
Principal Investigator

Walter Zahorodny
(973) 972-6577

Xiaobo Li

Erick Delgado
Research Assistant
(908) 812-3685

Contact Info
(201) 628-5188
University Height
Newark, NJ 07102


Biomedical Engineering Department @ NJIT